منابع مشابه
Tube Morphogenesis: No Pipe Dream in Drosophila
Tubular organs have characteristic lumen sizes that are generated during development. Recent studies of tubular systems in Drosophila have implicated intracellular vesicle transport as an important step in lumen expansion.
متن کاملTube Morphogenesis Making and Shaping Biological Tubes
Many organs are composed of epithelial tubes that transport vital fluids. Such tubular organs develop in many different ways and generate tubes of widely varying sizes and structures, but always with the apical epithelial surface lining the lumen. We describe recent progress in several diverse cell culture and genetic models of tube morphogenesis, which suggest apical membrane biogenesis, vesic...
متن کاملNeural tube morphogenesis in synthetic 3D microenvironments.
Three-dimensional organoid constructs serve as increasingly widespread in vitro models for development and disease modeling. Current approaches to recreate morphogenetic processes in vitro rely on poorly controllable and ill-defined matrices, thereby largely overlooking the contribution of biochemical and biophysical extracellular matrix (ECM) factors in promoting multicellular growth and reorg...
متن کاملMorphogenesis: Shroom in to Close the Neural Tube
A novel actin-binding protein, Shroom, localises to precisely those cells that will constrict during cranial neural tube closure and appears pivotal in regulating the apical constrictions that drive epithelial foldings in vertebrate embryos.
متن کاملAdvanced cardiac morphogenesis does not require heart tube fusion.
The bilateral cardiac mesoderm migrates from the lateral region of the embryo to the ventral midline, where it fuses to form the primitive heart tube. It is generally accepted that migration and fusion are essential for subsequent stages of cardiac morphogenesis. We present evidence that, in Foxp4 mutant embryonic mice, each bilateral heart-forming region is capable of developing into a highly ...
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ژورنال
عنوان ژورنال: Cell
سال: 2003
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(02)01283-7